Smaller, smarter, and personalized

Neuromodulation devices continue to break new ground, delivering more precise and personalized treatment, improved patient outcomes, and reduced side effects.

One-stop solution for neuromodulation innovation

Working with our team of implantable device experts, you are always one step ahead of the latest advances in neuromodulation technology, including:

  • Miniaturization that makes the device fit in smaller areas of the body, such as the ear or eye.
  • Wireless technology to deliver electrical stimulation with minimal invasion.
  • Software applications that allow providers and patients to control and customize stimulation for more effective personalized treatment and fewer side effects.
  • Real-time stimulation adjustment based on closed-loop feedback from the patient’s body or brain.
  • Algorithms that can learn from the patient’s response to the treatment and optimize the stimulation to increase efficacy over time.

Optimizing neuromodulation performance

Optimizing neuro-modulation performance

While specific performance requirements depend on the type of neuromodulation device and therapy delivered, neuromodulation IPGs share many common requirements:

Devices are expected to pack more functionality into smaller form factors that are easier to implant or fit onto the body surface.
The device must operate reliably over its expected lifetime, with an extremely low failure rate.
The device must be safe for implantation and use in the human body.

Implantable neuromodulation devices must be designed for ultra-low power consumption to reduce the frequency of device replacements in primary battery applications, and the frequency of patient charging in rechargeable devices.

The device must be easy to implant, adjust, and manage, with user-friendly interfaces for both the healthcare provider and the patient, and special attention must be paid to the patient experience with rechargeable devices.
The majority of implantable devices today support wirelessly-enabled cloud-based patient monitoring and data collection.

Result-based business model

Cash efficiency is a “do or die” proposition for any early stage company, and hourly-priced projects can quickly lead to cost and time overruns.

Our pricing is based on results, giving you the predictability you need to plan your budget and meet your funding milestones with confidence.

And with direct access to our project management system, you have real-time visibility into our progress so you always know where you are.

You pay for: Milestones completed

You don’t pay for: Our time

design for success

From napkin sketch to commercially-viable product, we take a holistic approach to product development, addressing all the required aspects for your device to be successful:

Ensuring the device can perform as required to deliver the intended clinical results

Ensuring the device can be operated in the intended clinical setting

Ensuring the design and development process is documented in compliance with ISO 13485:2016 and that the design meets the requirements imposed by relevant regulatory standards

Ensuring manufacturing is feasible within your business case assumptions and identifying qualified suppliers and manufacturing partners

Optimizing device cost of goods sold (COGS)

“Nocturnal understands the pressures and realities of operating an early stage medical device company. Their technical capabilities, collaborative process, and startup-friendly business model made working with them a true pleasure.”
Joe Passman, Sr. Principal R&D Engineer, NXT Biomedical


We don’t mean to make light of the challenges, but having “been there, done that” does make a difference. With proven neuromodulation expertise on your team, you’ll be ready to handle any unexpected twists and turns on your journey to commercial success.

Turn your sketch into reality.